Scientific Program
Thursday, April 15 - Adipobiology
15:00-15:10
 Opening Remarks
Hirofumi Makino Symposium Chair, Japan
Eberhard Ritz Symposium Co-Chair, Germany
15:10-16:20
 Opening Plenary Session
Chairs
Bernardo Rodríguez-Iturbe
Venezuela
Hirofumi Makino Japan
Speakers
1. Sudden death in end-stage kidney disease
Eberhard Ritz Germany
2. Adipocytokine and cardiovascular injury
Takashi Kadowaki Japan
16:20-18:00
 Adipocyte and the Kidney
Chairs
Agnes Fogo USA
Tsuyoshi Watanabe Japan
Speakers
1. Lipids, adipokines and CV mortality in ESRD patients
Christoph Wanner Germany
2. Body fat and survival in CKD
Tetsuo Shoji Japan
3. Adipocyte as a culprit of reno-cardiovascular injury
Hunjoo Ha Korea
4. Caloric imbalance and the kidney
Kumar Sharma USA
18:00-
 Opening Reception
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Friday, April 16 - Vascular Calcification
8:00-9:00
 Meet the Professor Breakfast
  Round-table style discussion
9:30-10:10
 Plenary Session
Chair
Hermann Haller Germany
Speaker
Recent advances in understanding interplays among the kidney, bone and vascular system
Tilman Drüeke France
10:10-11:25
 Calcification and Phosphate Biology
Chairs
Adeera Levin Canada
Yuh-Feng Lin Taiwan
Speakers
1. Molecular mechanisms of vascular calcification: possible involvement of FGF23
Takashi Shimada Japan
2. New insights into the pathogenesis of uremic vascular calcifications
Jürgen Floege Germany
3. Vascular calcification, aging, and beyond
Makoto Kuroo USA
11:30-12:25
 Vitamin D (sponsored by CHUGAI PHARMACEUTICAL CO., LTD.)
Chairs
Ravi Thadhani USA
Masafumi Fukagawa Japan
Speakers
1. Nutritional Vitamin D vs. Active Vitamin D: Which is needed in CKD patients?
Kamyar Kalantar-Zadeh USA
2. Significance of vitamin D on CKD patients
Takayuki Hamano USA
 Metabolic Syndrome 
 (sponsored by Nippon Boehringer Ingelheim Co., Ltd. / Astellas Pharma Inc.)
Chairs
Yasuhiko Tomino Japan
Suhnggwon Kim Korea
Speakers
1. New components of the renin-angiotensin system: relevance to diabetic nephropathy
Mark Cooper Australia
2. Next generation ARBs: new opportunities for preventing vascular injury and renal damage
Theodore Kurtz USA
12:30-14:00
 Poster Session
14:00-15:40
 Bone-Vascular Connection
Chairs
Tilman Drüeke France
Hai Yan Wang China
Speakers
1. Communication and interactions between blood vessels and bone
Grahame Elder Australia
2. Strategies to prevent or reverse the progression of vascular calcification in CKD
Ziad A Massy France
3. Fibroblast growth factor 23 and mortality among patients undergoing hemodialysis
Myles Wolf USA
4. Vitamin D, endothelial dysfunction and arterial stiffness in patients with chronic kidney disease
Gerard London France
15:40-16:00  Coffee Break
16:00-17:40
 Recent Diagnostic and Therapeutic Advances
Chairs
Carmine Zoccali Italy
Hiroshi Itoh Japan
Speakers
1. Role of HO-1 in AVF function in HD patients: Prognostic association with length polymorphism and regulatory mechanism for FIR therapy
Chih-Ching Lin Taiwan
2. Total body atherosclerosis assessment by MRI: Its links to biomarkers
Tobias Larsson Sweden
3. Effectiveness of hemodialysis access with an autologous tissue-engineered vascular graft
Todd N. McAllister USA
4. ASTRAL, a very large RCT of angioplasty and stenting for atheromatous renovascular disease
Philip Kalra UK
17:45-18:40
 Cardiotonic Substance (sponsored by Bayer Yakuhin, Ltd.)
Chairs
Sei Sasaki Japan
Gerard London France
Speakers
1. Endogenous cardiotonic steroids, salt-sensitivity of blood pressure, and chronic renal failure
Alexei Y Bagrov USA
2. Aldosterone and vascular injury
Hans Oberleithner Germany
3. Therapeutic impact on glomerular capillary failure: an integrative biology perspective.
Matthias Kretzler USA
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Saturday, April 17 - Oxygen Biology and Cardio-Renal Connection
8:00-9:00
 Meet the Professor Breakfast
  Round-table style discussion
9:30-10:10
 Plenary Session
Chair
Eberhard Ritz Germany
Speaker
Regeneration therapy for heart failure
Issei Komuro Japan
10:10-11:50
 Oxygen biology - Hypoxia and Oxidative stress
Chairs
Jürgen Floege Germany
Ton Rabelink Netherland
Speakers
1. Identification of novel targets of hypoxia-responsive pathways
Masaomi Nangaku Japan
2. The ying yang of hypoxia-inducible gene expression
Kai-Uwe Eckardt Germany
3. Oxidative stress: A new perspective for an old paradigm
Toshio Miyata Japan
4. Role of oxidative stress and inflammation in the progression of CKD
Bernardo Rodríguez-Iturbe
Venezuela
12:00-12:55
 Cardio-Renal Connection (sponsored by Novartis Pharma K.K.)
Chairs
Bernardo Rodríguez-Iturbe
Venezuela
Genjiro Kimura Japan
Speakers
1. Sodium as a culprit for cardio-renal syndrome
Akira Nishiyama Japan
2. Strain vessel: New hypothesis for the cardio-renal syndrome
Sadayoshi Ito Japan
 Renoprotection (sponsored by Daiichi-Sankyo)
Chairs
Herman Haller Germany
Kimio Tomita Japan
Speakers
1. ARB, endothelial function, and renoprotection
Danilo Fliser Germany
2. New horizon of RAS inhibition in therapy for type 2 diabetic nephropathy
Enyu Imai Japan
13:00-14:00
 Poster Session
14:00-15:40
 Cardio-Renal Syndrome
Chairs
Mark Cooper Australia
Alan Go USA
Speakers
1. Endotoxemia, inflammation and cardiovascular disease in CKD patients
Philip Li Hong-Kong
2. Reducing albuminuria: an effective way to prevent renal and cardiovascular disease
Fan Fan Hou China
3. Left ventricular hypertrophy and myocardiopathy in CKD
Carmine Zoccali Italy
4. How to face the deadly triad of cardiovascular disease, chronic kidney disease and diabetes mellitus in clinical practice
Adeera Levin Canada
15:40-16:10  Coffee Break
16:10-17:50
 Promising Target Molecules for Future Therapy
Chairs
Charles van Ypersele de Strihou
Belgium
Chih-Wei Yang Taiwan
Speakers
1. Targets for vascular damage: Insights from Mendelian disorders and genome-wide association studies
Oliver Devuyst Belgium
2. PAI-1 as a culprit for cardio-renal syndrome and beyond
Douglas Vaughan USA
3. Is ADMA a modifiable risk factor in cardiovascular and renal diseases?
James Leiper UK
4. Aldosterone and cardio-renal injury
Toshiro Fujita Japan
17:55-18:50
 Anemia (sponsored by Kyowa Hakko Kirin Co., Ltd.)
Chairs
Tadao Akizawa Japan
Kai-Uwe Eckardt Germany
Speakers
1. Japanese CKD features elucidated by the CKD-JAC
Seiichi Matsuo Japan
2. Latest perspectives on outcomes of ESA therapy in CKD
Robert Toto USA
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Sunday, April 18 - Vascular Senescence
8:30-9:10
 Plenary Session
Chair
Kumar Sharma USA
Speaker
Impact of kidney function on atherothrombotic complications in the general population and in patients with heart disease
Alan Go USA
9:10-10:25
 Vascular Injury and Regeneration
Chairs
Kosaku Nitta Japan
Oliver Devuyst Belgium
Speakers
1. New insights for cardiovascular injury in CKD
Valentina Kon USA
2. PPAR-gamma and CKD
Agnes Fogo USA
3. Microvascular remodeling and progression of renal failure
Ton Rabelink Netherland
10:25-11:40
 Vascular Ageing and Senescence
Chairs
Danilo Fliser Germany
Naoki Kashihara Japan
Speakers
1. Advanced glycation (AGEs) and cardio-renal ageing
Josephine Forbes Australia
2. RAS inhibition and longevity
Ariela Benigni Italy
3. Premature Vascular Senescence: the decline and fall of blood vessels
Michael Goligorsky USA
11:40
 Closing Remark
Tadao Akizawa Symposium Co-Chair, Japan
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